Kort
Fructosamines zijn eiwitten (in hoofdzaak albumine) waar glucose op onomkeerbare wijze aan gebonden is. De concentratie ervan weerspiegelt de bloedglucoseconcentratie over de afgelopen weken en is daarmee een tool in de opvolging van diabetes mellitus.
Diersoorten en referenties
Ezel
µmol/L
Fret
125 - 200
µmol/L
Hond
µmol/L
Normaal: 244 - 376
Diabetes nieuwe diagnose >400
Diabetescontrole
Goed <450
Matig <550
Slecht >550
Kat
µmol/L
Normaal: 222 - 359
Diabetes nieuwe diagnose >400
Diabetescontrole
Goed <450
Matig <550
Slecht >550
Konijn
µmol/L
Paard
281 - 374
µmol/L
Rund
µmol/L
Kenmerken
Afkorting
FRA
Rubriek
Glucose
LOINC
Methode
Colorimetric
Doorlooptijd
dezelfde dag
Staalname
*
Serum
EDTA plasma
Li-Heparine plasma
* = voorkeur
Laatst geupdate op 18 september 2026 om 01:00
Referenties
1.
Thoresen S, Bredal W. Clinical usefulness of fructosamine measurements in diagnosing and monitoring feline diabetes mellitus. J Small Anim Pract. 1996;37(2):64-68. [PubMed]
2.
Crenshaw K, Peterson M, Heeb L, Moroff S, Nichols R. Serum fructosamine concentration as an index of glycemia in cats with diabetes mellitus and stress hyperglycemia. J Vet Intern Med. 1996;10(6):360-364. [PubMed]
3.
Lutz T, Rand J, Ryan E. Fructosamine concentrations in hyperglycemic cats. Can Vet J. 1995;36(3):155-159. [PubMed]
4.
Loste A, Marca M, Pérez M, Unzueta A. Clinical value of fructosamine measurements in non-healthy dogs. Vet Res Commun. 2001;25(2):109-115. [PubMed]
5.
Mellanby R, Herrtage M. Insulinoma in a normoglycaemic dog with low serum fructosamine. J Small Anim Pract. 2002;43(11):506-508. [PubMed]
6.
Rijnberk A, S. Kooistra H. Clinical Endocrinology of Dogs and Cats. European Mathematical Society; 2010.
7.
Gilor C, Graves T, Lascelles B, Thomson A, Simpson W, Halpern D. The effects of body weight, body condition score, sex, and age on serum fructosamine concentrations in clinically healthy cats. Vet Clin Pathol. 2010;39(3):322-328. [PubMed]
8.
Reusch C, Haberer B. Evaluation of fructosamine in dogs and cats with hypo- or hyperproteinaemia, azotaemia, hyperlipidaemia and hyperbilirubinaemia. Vet Rec. 2001;148(12):370-376. [PubMed]
9.
Thoresen S, Bredal W. An evaluation of serum fructosamine as a marker of the duration of hypoproteinaemic conditions in dogs. Vet Res Commun. 1998;22(3):167-177. [PubMed]
10.
Reusch C, Tomsa K. Serum fructosamine concentration in cats with overt hyperthyroidism. J Am Vet Med Assoc. 1999;215(9):1297-1300. [PubMed]
11.
Zeugswetter F, Kleiter M, Wolfesberger B, Schwendenwein I, Miller I. Elevated fructosamine concentrations caused by IgA paraproteinemia in two dogs. J Vet Sci. 2010;11(4):359-361. [PubMed]
12.
J. Kaneko J, W. Harvey J, Bruss M. Clinical Biochemistry of Domestic Animals. Academic Press; 2008.
13.
D. Willard M, Tvedten H. Small Animal Clinical Diagnosis by Laboratory Methods. W B Saunders Company; 2004.
14.
Sonntag O, Scholer A. Drug interference in clinical chemistry: recommendation of drugs and their concentrations to be used in drug interference studies. Ann Clin Biochem. 2001;38(Pt 4):376-385. [PubMed]
15.
Link K, Rand J. Changes in blood glucose concentration are associated with relatively rapid changes in circulating fructosamine concentrations in cats. J Feline Med Surg. 2008;10(6):583-592. [PubMed]
Recent op pubmed
Hond
- Reusch, CE, Haberer, B. Evaluation of fructosamine in dogs and cats with hypo- or hyperproteinaemia, azotaemia, hyperlipidaemia and hyperbilirubinaemia. Vet Rec. 2001;148 (12):370-6. doi: 10.1136/vr.148.12.370. PubMed PMID:11321552 .
- Norris, O, Schermerhorn, T. Relationship between HbA1c, fructosamine and clinical assessment of glycemic control in dogs. PLoS One. 2022;17 (2):e0264275. doi: 10.1371/journal.pone.0264275. PubMed PMID:35213623 PubMed Central PMC8880912.
- An, JH, Ko, BG, Namkung, H, Lee, HG, Lim, HW, Huh, W et al.. Differential glycemic effects of DWP16001 in diabetic dogs according to baseline glycemic status: a multicenter randomized controlled trial. BMC Vet Res. 2025;21 (1):512. doi: 10.1186/s12917-025-04962-y. PubMed PMID:40796840 PubMed Central PMC12341280.
- Webb, CB. Troubleshooting the diabetic small animal patient. Clin Tech Small Anim Pract. 2002;17 (2):79-85. doi: 10.1053/svms.2002.33037. PubMed PMID:12219721 .
- Muñoz-Prieto, A, Escribano, D, Cerón, JJ, Martínez-Subiela, S, Tvarijonaviciute, A. Glucose, fructosamine, and insulin measurements in saliva of dogs: variations after an experimental glucose administration. Domest Anim Endocrinol. 2019;66 :64-71. doi: 10.1016/j.domaniend.2018.10.002. PubMed PMID:30472034 .
- Willesen, JL, Jensen, AL, Kristensen, AT, Kjelgaard-Hansen, M, Jessen, R, Koch, J et al.. Serum fructosamine concentrations in 59 dogs naturally Infected with Angiostrongylus vasorum. J Vet Med A Physiol Pathol Clin Med. 2006;53 (5):266-9. doi: 10.1111/j.1439-0442.2006.00828.x. PubMed PMID:16737518 .
- Watanabe, D, Nakara, H, Akagi, K, Ishii, T, Mizuguchi, H, Nagashima, Y et al.. Oral glucose tolerance test and determination of serum fructosamine level in beagle dogs. J Toxicol Sci. 2004;29 (1):33-6. doi: 10.2131/jts.29.33. PubMed PMID:15018152 .
- Loste, A, Marca, MC. Fructosamine and glycated hemoglobin in the assessment of glycaemic control in dogs. Vet Res. 2001;32 (1):55-62. doi: 10.1051/vetres:2001109. PubMed PMID:11254177 .
- Oikonomidis, IL, Daravigka, A, Ceron, JJ, Tvarijonaviciute, A, Lambrou, F, Tzenetidou, Z et al.. Glycated haemoglobin and serum fructosamine concentrations in sick, non-diabetic dogs receiving oral prednisolone. Vet Rec. 2025;196 (2):e4843. doi: 10.1002/vetr.4843. PubMed PMID:39618192 PubMed Central PMC11740410.
- Ottka, C, Puurunen, J, Müller, E, Weber, C, Klein, R, Lohi, H et al.. Metabolic changes associated with two endocrine abnormalities in dogs: elevated fructosamine and low thyroxine. Metabolomics. 2022;18 (8):58. doi: 10.1007/s11306-022-01917-4. PubMed PMID:35859216 PubMed Central PMC9300525.
Kat
- Hadd, MJ, Bienhoff, SE, Little, SE, Geller, S, Ogne-Stevenson, J, Dupree, TJ et al.. Safety and effectiveness of the sodium-glucose cotransporter inhibitor bexagliflozin in cats newly diagnosed with diabetes mellitus. J Vet Intern Med. 2023;37 (3):915-924. doi: 10.1111/jvim.16730. PubMed PMID:37148170 PubMed Central PMC10229323.
- Reusch, CE, Haberer, B. Evaluation of fructosamine in dogs and cats with hypo- or hyperproteinaemia, azotaemia, hyperlipidaemia and hyperbilirubinaemia. Vet Rec. 2001;148 (12):370-6. doi: 10.1136/vr.148.12.370. PubMed PMID:11321552 .
- Lutz, TA, Rand, JS, Ryan, E. Fructosamine concentrations in hyperglycemic cats. Can Vet J. 1995;36 (3):155-9. . PubMed PMID:7757920 PubMed Central PMC1686902.
- Webb, CB. Troubleshooting the diabetic small animal patient. Clin Tech Small Anim Pract. 2002;17 (2):79-85. doi: 10.1053/svms.2002.33037. PubMed PMID:12219721 .
- Pérez-López, L, Boronat, M, Melián, C, Brito-Casillas, Y, Wägner, AM. Kidney function and glucose metabolism in overweight and obese cats. Vet Q. 2020;40 (1):132-139. doi: 10.1080/01652176.2020.1759844. PubMed PMID:32315583 PubMed Central PMC7241541.
- Berman, CF, Lobetti, RG, Zini, E, Fosgate, GT, Schoeman, JP. Influence of high-protein and high-carbohydrate diets on serum lipid and fructosamine concentrations in healthy cats. J Feline Med Surg. 2022;24 (8):759-769. doi: 10.1177/1098612X211047062. PubMed PMID:34605307 PubMed Central PMC10812288.
- Kennedy, A, White, J, Lam, A, Kenny, P. Hypersomatotropism in diabetic cats in Australia. J Feline Med Surg. 2025;27 (11):1098612X251379726. doi: 10.1177/1098612X251379726. PubMed PMID:41215559 PubMed Central PMC12605907.
- Tobin, S, Mott, J, Gilor, C. Evaluating the correlation between serum fructosamine concentration and interstitial glucose concentration in cats with diabetes mellitus. J Vet Intern Med. 2026;40 (3):. doi: 10.1093/jvimsj/aalag104. PubMed PMID:42224493 PubMed Central PMC13225269.
- Bennett, N. Monitoring techniques for diabetes mellitus in the dog and the cat. Clin Tech Small Anim Pract. 2002;17 (2):65-9. doi: 10.1053/svms.2002.33044. PubMed PMID:12219718 .
- Kieler, IN, Osto, M, Hugentobler, L, Puetz, L, Gilbert, MTP, Hansen, T et al.. Diabetic cats have decreased gut microbial diversity and a lack of butyrate producing bacteria. Sci Rep. 2019;9 (1):4822. doi: 10.1038/s41598-019-41195-0. PubMed PMID:30886210 PubMed Central PMC6423039.
Paard
- Knowles, EJ, Menzies-Gow, NJ, Mair, TS. Plasma fructosamine concentrations in horses with pituitary pars intermedia dysfunction with and without laminitis. Equine Vet J. 2014;46 (2):249-51. doi: 10.1111/evj.12090. PubMed PMID:23663105 .
- Ribeiro, RM, Ribeiro, DS, Cota, LO, Leme, FO, M Carvalho, A, Faleiros, RR et al.. Changes in metabolic and physiological biomarkers in Mangalarga Marchador horses with induced obesity. Vet J. 2021;270 :105627. doi: 10.1016/j.tvjl.2021.105627. PubMed PMID:33641803 .
- Knowles, EJ, Withers, JM, Mair, TS. Increased plasma fructosamine concentrations in laminitic horses. Equine Vet J. 2012;44 (2):226-9. doi: 10.1111/j.2042-3306.2011.00419.x. PubMed PMID:21696439 .
- Murphy, D, Reid, SW, Graham, PA, Love, S. Fructosamine measurement in ponies: validation and response following experimental cyathostome infection. Res Vet Sci. 1997;63 (2):113-8. doi: 10.1016/s0034-5288(97)90002-3. PubMed PMID:9429242 .
- Satué, K, Marcilla, M, Medica, P, Cravana, C, Fazio, E. Temporal relationships of GH, IGF-I and fructosamine concentrations in pregnant Spanish Purebred mares: A substantial contribution from the hormonal standpoint. Theriogenology. 2018;118 :164-171. doi: 10.1016/j.theriogenology.2018.05.040. PubMed PMID:29909261 .
- Satué, K, Fazio, E, Velasco-Martínez, MG, Barbiera, G, La Fauci, D. Differential profiles of GH, IGF-1, and fructosamine in follicular fluid and plasma of cyclic mares. Domest Anim Endocrinol. 2026;95 :107000. doi: 10.1016/j.domaniend.2026.107000. PubMed PMID:41666841 .
- Gehlen, H, Twickel, S, Stöckle, S, Weber, C, Bartmann, CP. Diagnostic orientation values for ACTH and other parameters for clinically healthy donkeys and mules (insulin, triglycerides, glucose, fructosamines, and ɣ-GT). J Anim Physiol Anim Nutr (Berl). 2020;104 (2):679-689. doi: 10.1111/jpn.13279. PubMed PMID:31900994 .
- Staudacher, G. [Fructosamine as a valuable criterion for the evaluation of diabetic animals and its photometric determination]. Tierarztl Prax. 1990;18 (5):441-6. . PubMed PMID:2264046 .
- Keen, JA, McLaren, M, Chandler, KJ, McGorum, BC. Biochemical indices of vascular function, glucose metabolism and oxidative stress in horses with equine Cushing's disease. Equine Vet J. 2004;36 (3):226-9. doi: 10.2746/0425164044877215. PubMed PMID:15147129 .
- Murphy, D, Love, S. The pathogenic effects of experimental cyathostome infections in ponies. Vet Parasitol. 1997;70 (1-3):99-110. doi: 10.1016/s0304-4017(96)01153-3. PubMed PMID:9195714 .