Kort
Fructosamines zijn eiwitten (in hoofdzaak albumine) waar glucose op onomkeerbare wijze aan gebonden is. De concentratie ervan weerspiegelt de bloedglucoseconcentratie over de afgelopen weken en is daarmee een tool in de opvolging van diabetes mellitus.
Diersoorten en referenties
Ezel
µmol/L
Fret
125 - 200
µmol/L
Hond
µmol/L
Normaal: 244 - 376
Diabetes nieuwe diagnose >400
Diabetescontrole
Goed <450
Matig <550
Slecht >550
Kat
µmol/L
Normaal: 222 - 359
Diabetes nieuwe diagnose >400
Diabetescontrole
Goed <450
Matig <550
Slecht >550
Konijn
µmol/L
Paard
281 - 374
µmol/L
Rund
µmol/L
Kenmerken
Afkorting
FRA
Rubriek
Glucose
LOINC
Methode
Colorimetric
Doorlooptijd
dezelfde dag
Staalname
*
Serum
EDTA plasma
Li-Heparine plasma
* = voorkeur
Laatst geupdate op 9 januari 2023 om 01:00
Referenties
1.
Thoresen S, Bredal W. Clinical usefulness of fructosamine measurements in diagnosing and monitoring feline diabetes mellitus. J Small Anim Pract. 1996;37(2):64-68. [PubMed]
2.
Crenshaw K, Peterson M, Heeb L, Moroff S, Nichols R. Serum fructosamine concentration as an index of glycemia in cats with diabetes mellitus and stress hyperglycemia. J Vet Intern Med. 1996;10(6):360-364. [PubMed]
3.
Lutz T, Rand J, Ryan E. Fructosamine concentrations in hyperglycemic cats. Can Vet J. 1995;36(3):155-159. [PubMed]
4.
Loste A, Marca M, Pérez M, Unzueta A. Clinical value of fructosamine measurements in non-healthy dogs. Vet Res Commun. 2001;25(2):109-115. [PubMed]
5.
Mellanby R, Herrtage M. Insulinoma in a normoglycaemic dog with low serum fructosamine. J Small Anim Pract. 2002;43(11):506-508. [PubMed]
6.
Rijnberk A, S. Kooistra H. Clinical Endocrinology of Dogs and Cats. European Mathematical Society; 2010.
7.
Gilor C, Graves T, Lascelles B, Thomson A, Simpson W, Halpern D. The effects of body weight, body condition score, sex, and age on serum fructosamine concentrations in clinically healthy cats. Vet Clin Pathol. 2010;39(3):322-328. [PubMed]
8.
Reusch C, Haberer B. Evaluation of fructosamine in dogs and cats with hypo- or hyperproteinaemia, azotaemia, hyperlipidaemia and hyperbilirubinaemia. Vet Rec. 2001;148(12):370-376. [PubMed]
9.
Thoresen S, Bredal W. An evaluation of serum fructosamine as a marker of the duration of hypoproteinaemic conditions in dogs. Vet Res Commun. 1998;22(3):167-177. [PubMed]
10.
Reusch C, Tomsa K. Serum fructosamine concentration in cats with overt hyperthyroidism. J Am Vet Med Assoc. 1999;215(9):1297-1300. [PubMed]
11.
Zeugswetter F, Kleiter M, Wolfesberger B, Schwendenwein I, Miller I. Elevated fructosamine concentrations caused by IgA paraproteinemia in two dogs. J Vet Sci. 2010;11(4):359-361. [PubMed]
12.
J. Kaneko J, W. Harvey J, Bruss M. Clinical Biochemistry of Domestic Animals. Academic Press; 2008.
13.
D. Willard M, Tvedten H. Small Animal Clinical Diagnosis by Laboratory Methods. W B Saunders Company; 2004.
14.
Sonntag O, Scholer A. Drug interference in clinical chemistry: recommendation of drugs and their concentrations to be used in drug interference studies. Ann Clin Biochem. 2001;38(Pt 4):376-385. [PubMed]
15.
Link K, Rand J. Changes in blood glucose concentration are associated with relatively rapid changes in circulating fructosamine concentrations in cats. J Feline Med Surg. 2008;10(6):583-592. [PubMed]
Recent op pubmed
Hond
- Norris, O, Schermerhorn, T. Relationship between HbA1c, fructosamine and clinical assessment of glycemic control in dogs. PLoS One. 2022;17 (2):e0264275. doi: 10.1371/journal.pone.0264275. PubMed PMID:35213623 PubMed Central PMC8880912.
- Reusch, CE, Haberer, B. Evaluation of fructosamine in dogs and cats with hypo- or hyperproteinaemia, azotaemia, hyperlipidaemia and hyperbilirubinaemia. Vet Rec. 2001;148 (12):370-6. doi: 10.1136/vr.148.12.370. PubMed PMID:11321552 .
- Muñoz-Prieto, A, Escribano, D, Cerón, JJ, Martínez-Subiela, S, Tvarijonaviciute, A. Glucose, fructosamine, and insulin measurements in saliva of dogs: variations after an experimental glucose administration. Domest Anim Endocrinol. 2019;66 :64-71. doi: 10.1016/j.domaniend.2018.10.002. PubMed PMID:30472034 .
- Ottka, C, Puurunen, J, Müller, E, Weber, C, Klein, R, Lohi, H et al.. Metabolic changes associated with two endocrine abnormalities in dogs: elevated fructosamine and low thyroxine. Metabolomics. 2022;18 (8):58. doi: 10.1007/s11306-022-01917-4. PubMed PMID:35859216 PubMed Central PMC9300525.
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- Zeugswetter, FK, Beer, R, Schwendenwein, I. Evaluation of fructosamine concentration as an index marker for glycaemic control in diabetic dogs. Vet Rec. 2022;190 (2):e244. doi: 10.1002/vetr.244. PubMed PMID:33870504 .
- Loste, A, Marca, MC. Fructosamine and glycated hemoglobin in the assessment of glycaemic control in dogs. Vet Res. 2001;32 (1):55-62. doi: 10.1051/vetres:2001109. PubMed PMID:11254177 .
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- Reusch, CE, Liehs, MR, Hoyer, M, Vochezer, R. Fructosamine. A new parameter for diagnosis and metabolic control in diabetic dogs and cats. J Vet Intern Med. 1993;7 (3):177-82. doi: 10.1111/j.1939-1676.1993.tb03183.x. PubMed PMID:8331612 .
Kat
- Reusch, CE, Haberer, B. Evaluation of fructosamine in dogs and cats with hypo- or hyperproteinaemia, azotaemia, hyperlipidaemia and hyperbilirubinaemia. Vet Rec. 2001;148 (12):370-6. doi: 10.1136/vr.148.12.370. PubMed PMID:11321552 .
- Berman, CF, Lobetti, RG, Zini, E, Fosgate, GT, Schoeman, JP. Influence of high-protein and high-carbohydrate diets on serum lipid and fructosamine concentrations in healthy cats. J Feline Med Surg. 2022;24 (8):759-769. doi: 10.1177/1098612X211047062. PubMed PMID:34605307 .
- Pérez-López, L, Boronat, M, Melián, C, Brito-Casillas, Y, Wägner, AM. Kidney function and glucose metabolism in overweight and obese cats. Vet Q. 2020;40 (1):132-139. doi: 10.1080/01652176.2020.1759844. PubMed PMID:32315583 PubMed Central PMC7241541.
- Benedict, SL, Mahony, OM, McKee, TS, Bergman, PJ. Evaluation of bexagliflozin in cats with poorly regulated diabetes mellitus. Can J Vet Res. 2022;86 (1):52-58. . PubMed PMID:34975223 PubMed Central PMC8697324.
- Reusch, CE, Liehs, MR, Hoyer, M, Vochezer, R. Fructosamine. A new parameter for diagnosis and metabolic control in diabetic dogs and cats. J Vet Intern Med. 1993;7 (3):177-82. doi: 10.1111/j.1939-1676.1993.tb03183.x. PubMed PMID:8331612 .
- Kieler, IN, Osto, M, Hugentobler, L, Puetz, L, Gilbert, MTP, Hansen, T et al.. Diabetic cats have decreased gut microbial diversity and a lack of butyrate producing bacteria. Sci Rep. 2019;9 (1):4822. doi: 10.1038/s41598-019-41195-0. PubMed PMID:30886210 PubMed Central PMC6423039.
- Crenshaw, KL, Peterson, ME, Heeb, LA, Moroff, SD, Nichols, R. Serum fructosamine concentration as an index of glycemia in cats with diabetes mellitus and stress hyperglycemia. J Vet Intern Med. 1996;10 (6):360-4. doi: 10.1111/j.1939-1676.1996.tb02081.x. PubMed PMID:8947867 .
- Lutz, TA, Rand, JS, Ryan, E. Fructosamine concentrations in hyperglycemic cats. Can Vet J. 1995;36 (3):155-9. . PubMed PMID:7757920 PubMed Central PMC1686902.
- Hoenig, M, Traas, AM, Schaeffer, DJ. Evaluation of routine hematology profile results and fructosamine, thyroxine, insulin, and proinsulin concentrations in lean, overweight, obese, and diabetic cats. J Am Vet Med Assoc. 2013;243 (9):1302-9. doi: 10.2460/javma.243.9.1302. PubMed PMID:24134581 .
- Gostelow, R, Scudder, C, Keyte, S, Forcada, Y, Fowkes, RC, Schmid, HA et al.. Pasireotide Long-Acting Release Treatment for Diabetic Cats with Underlying Hypersomatotropism. J Vet Intern Med. 2017;31 (2):355-364. doi: 10.1111/jvim.14662. PubMed PMID:28145031 PubMed Central PMC5354018.
Paard
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- Ribeiro, RM, Ribeiro, DS, Cota, LO, Leme, FO, M Carvalho, A, Faleiros, RR et al.. Changes in metabolic and physiological biomarkers in Mangalarga Marchador horses with induced obesity. Vet J. 2021;270 :105627. doi: 10.1016/j.tvjl.2021.105627. PubMed PMID:33641803 .
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- Satué, K, Marcilla, M, Medica, P, Cravana, C, Fazio, E. Temporal relationships of GH, IGF-I and fructosamine concentrations in pregnant Spanish Purebred mares: A substantial contribution from the hormonal standpoint. Theriogenology. 2018;118 :164-171. doi: 10.1016/j.theriogenology.2018.05.040. PubMed PMID:29909261 .
- Gehlen, H, Twickel, S, Stöckle, S, Weber, C, Bartmann, CP. Diagnostic orientation values for ACTH and other parameters for clinically healthy donkeys and mules (insulin, triglycerides, glucose, fructosamines, and ɣ-GT). J Anim Physiol Anim Nutr (Berl). 2020;104 (2):679-689. doi: 10.1111/jpn.13279. PubMed PMID:31900994 .
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- Staudacher, G. [Fructosamine as a valuable criterion for the evaluation of diabetic animals and its photometric determination]. Tierarztl Prax. 1990;18 (5):441-6. . PubMed PMID:2264046 .